抄録
Typical pictures of the premortal enlargement of mitochondria were ob-served in liver of guinea pigs dying from experimental scurvy. Though not typical, similar pictures were also obtained in livers of mice dying from injection of Shigella dysenteriae exotoxin. Pentosenucleic aid (PNA) content of the average liver cell decreased considerably in livers of rats dying of prolonged starvation but remained unchanged in scurvy-dying guinea pig livers, the both cases showing mitochondria typically enlarged. Thus, the decrease in PNA content of the liver cell can not be one of the necessary conditions for the premortal enlargement of hepatic mitochondria. These and additional data on livers with different patterns of cytoplasmic basophilia indicate that the type of basophilia should not be taken as index of PNA content of the liver cell, though it may well be of great morphologic significance.
