A New Sublive of Ehrlich Ascites Tumor: Hypertriploid

Abstract

A hypertriploid subline of Ehrlich ascites tumor, having a modal chromosome number at 65, was discovered in this laboratory. This new subline shows a much higher degree of virulence than the fast-killing hypotetraploid subline which has been known to be the most malignant of all Ehrlich ascites tumors. By the chromosome morphology study, it is further substantiated as a subline of Ehrlich ascites tumor. The biological and biochemical characteristics of this hypertriploid subline have been investigated. Its pattern of respiratory activities is different from other Ehrlich ascites tumor sublines reported.