The Japanese Journal of Dermatology
Online ISSN : 1346-8146
Print ISSN : 0021-499X
ISSN-L : 0021-499X
Original Articles
A Case of Squamous Cell Carcinoma with Varied Histological Patterns and Cytokeratin Expression
Mayuko NagaoTakafumi KadonoMayumi KomineKanako KikuchiKunihiko TamakiTakeo MaekawaJunichiro SikadaHironobu Ihn
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2008 Volume 118 Issue 6 Pages 1079-1083

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Abstract

We describe a 60-year-old man with squamous cell carcinoma. The histology of the tumor included varied patterns, which were mainly classified into three types. Furthermore, we also confirmed the differentiation of each type using immunochemical studies of cytokeratine. Such immunochemical studies are very useful for determining the origins of cells and supporting the diagnosis. Tumor cells show varied immunochemical patterns depending on their differentiation. Thorough immunochemical studies are useful for disclosing and diagnosing the origin of the tumor, This report suggests that such a diagnosis requires consideration of the entire tumor.

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© 2008 Japanese Dermatological Association
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