頭部血管肉腫の血気胸に対するPaclitaxel胸腔内投与の有効性

渡会 晃; 増澤 幹男; 長橋 和矢; 山本 都美; 天羽 康之; 白井 京美; 齊藤 典充; 坪井 廣美; 黒岩 裕美; 勝岡 憲生

doi:10.14924/dermatol.118.1241

Original Articles

Intrapleural Paclitaxel Injection for a Scalp-Hemangiosarcoma Patient with Hemopneumothorax

Akira Watarai, Mikio Masuzawa, Kazuya Nagahashi, Tomi Yamamoto, Yasuyuki Amoh, Kyomi Shirai, Norimitu Saito, Hiromi Tuboi, Yumi Kuroiwa, Kensei Katuoka

Author information

Akira Watarai
Department of Dermatology, Kitasato University School of Medicine
Mikio Masuzawa
Department of Dermatology, Kitasato University School of Medicine
Kazuya Nagahashi
Department of Dermatology, Kitasato University School of Medicine
Tomi Yamamoto
Department of Dermatology, Kitasato University School of Medicine
Yasuyuki Amoh
Department of Dermatology, Kitasato University School of Medicine
Kyomi Shirai
Department of Dermatology, Kitasato University School of Medicine
Norimitu Saito
Department of Dermatology, Kitasato University School of Medicine
Hiromi Tuboi
Department of Dermatology, National Hospital Organization Yokohama Medical Center
Yumi Kuroiwa
Department of Pulmonary Medicine, Kitasato University of Medicine
Kensei Katuoka
Department of Dermatology, Kitasato University School of Medicine

Keywords: Angiosarcoma, hemopneumothorax, intrapleural paclitaxel injection

JOURNAL RESTRICTED ACCESS

2008 Volume 118 Issue 7 Pages 1241-1245

DOI https://doi.org/10.14924/dermatol.118.1241

Details

Abstract

We treated a case of hemopneumothorax in 74-year-old man with hemangiosarcoma of the scalp by intrapleural injection of Paclitaxel. This administration is the first trial with Paclitaxel. The drug transition into the blood flow was at a very low concentration. Slight pleural pain and delayed neutropenia were observed, but the treatment was well tolerated. The hemopneumothorax has not recurred in more than ten months since the treatment. We suggest that this therapy can be useful for hemopneumothorax caused by hemangiosarcoma.

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