A Case of Systemic Lupus Erythematosus Accompanied by Intractable Perforation of the Small Intestine and Thrombosis of the Inferior Vena Cava

Abstract

A 48-year-old female with a 15 year history of systemic lupus erythematosus was referred to our department in August of 2005 because of the facial edema and multiple ulcerated erythema. Methylprednisolone pulse therapy was effective in treating her symptoms; however, her small intestine repeatedly perforated during the reduction of the prednisolone dose. Conservative therapy finally led to a successful outcome, although lupus enteritis recurred several times and a thrombosis of the inferior vena cava was also found. Although intestinal perforation is rare in SLE, we should always be aware of the possibility when SLE patients report acute abdominal symptoms.