Three Rare Cases of Cutaneous Angiosarcoma on the Cheek or the Back

Abstract

Cutaneous angiosarcoma (CA) is a rare soft tissue sarcoma that typically occurs on the head and neck, particularly on the scalp. It is more common in older patients, and it has a poor prognosis. This report presents three rare cases of CA that appeared on the cheek and the back. The first case was a male with CA on the cheek, and he had liver metastasis. Although he received hepatic intra-arterial infusion therapy with recombinant interleukin-2 and paclitaxel or docetaxel, the therapeutic efficacy was poor. The second and the third cases were males with CA on the trunk. They received several types of treatment; there were no recurrences and no metastases during the observation periods. However, one of them died from acute exacerbation of interstitial pneumonia during chemotherapy and radiation therapy. Herein we report our latest therapeutic observations in patients with CA: hepatic intra-arterial infusion therapy, the feature of CA on the trunk, and the risk of interstitial pneumonia during radiation and chemotherapy for CA.