Clinical Features of Three Cases of Dermatomyositis with Anti-SRP Antibody

Abstract

Using anti-SRP antibody, we examined the clinical features of 3 cases of dermatomyositis who visited our hospital. The average age of these 3 patients was 57 years and all the cases were female. All 3 patients had Gottron's sign on their hands as a common skin manifestation. They all suffered from muscle weakness and the myogenic enzymes, creatine kinase and aldolase were elevated. Interstitial lung disease and a malignant tumor were each found in 1 of the 3 cases. One patient was treated solely systemic administration of corticosteroid and the remaining 2 patients received a combination therapy of corticosteroid and an immunosuppressive agent. All their symptoms were resolved, and their conditions came under control.