Dental Materials Journal
Online ISSN : 1881-1361
Print ISSN : 0287-4547
Original Paper
Calcification of MC3T3-E1 cells on titanium and zirconium
Takayuki UMEZAWAPeng CHENYusuke TSUTSUMIHisashi DOIMaki ASHIDAShoichi SUZUKIKeiji MORIYAMATakao HANAWA
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Volume 34 (2015) Issue 5 Pages 713-718

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Abstract

To confirm similarity of hard tissue compatibility between titanium and zirconium, calcification of MC3T3-E1 cells on titanium and zirconium was evaluated in this study. Mirror-polished titanium (Ti) and zirconium (Zr) disks and zirconium-sputter deposited titanium (Zr/Ti) were employed in this study. The surface of specimens were characterized using scanning electron microscopy and X-ray diffraction. Then, the cellular proliferation, differentiation and calcification of MC3T3-E1 cells on specimens were investigated. The surface of Zr/Ti was much smoother and cleaner than those of Ti and Zr. The proliferation of the cell was the same among three specimens, while the differentiation and calcification on Zr/Ti were faster than those on Ti and Zr. Therefore, Ti and Zr showed the identical hard tissue compatibility according to the evaluation with MC3T3-E1 cells. Sputter deposition may improve cytocompatibility.

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© 2015 The Japanese Society for Dental Materials and Devices
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