Dental Materials Journal
Online ISSN : 1881-1361
Print ISSN : 0287-4547
ISSN-L : 0287-4547
Original Paper
Bone augmentation around a dental implant using demineralized bone sheet containing biologically active substances
Mai SHIRAIRyuji YAMAMOTOToshie CHIBAKoichiro KOMATSUShinji SHIMODAYasuo YAMAKOSHIShinichiro OIDAChikahiro OHKUBO
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2016 Volume 35 Issue 3 Pages 470-478

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Abstract

This study was designed to evaluate the volume of alveolar bone augmentation after immediate implant placement using demineralized bone. We examined the collagen matrix of demineralized bone and biologically active substances contained therein. Rat maxillary first molars were extracted, and the animals were divided into five groups as follows: tooth extraction only, implant into the mesial root socket, implant and other root sockets covered with demineralized bone sheet, implant and other root sockets filled with demineralized bone powder under the sheet, and implant and other root sockets covered with demineralized bone sheet from which proteins were extracted. We ascertained whether biologically active substances are contained in extracted proteins. Biologically active substances were detected in extracted proteins. Conditions using demineralized bone sheet with biologically active substances significantly augmented the height of the alveolar bone. Such resorbable membranes containing biologically active substances hold promise as clinical agents for bone augmentation upon implantation.

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© 2016 The Japanese Society for Dental Materials and Devices
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