Dental Materials Journal
Online ISSN : 1881-1361
Print ISSN : 0287-4547
ISSN-L : 0287-4547
Original Paper
Inhibitory effect of zinc-containing desensitizer on bacterial biofilm formation and root dentin demineralization
Amr SAADToru NIKAIDOAhmed ABDOUKhairul MATINMichael F. BURROWJunji TAGAMI
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2019 Volume 38 Issue 6 Pages 940-946

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Abstract

This study compared the effect of a novel zinc containing, Caredyne Shield (CS), and a fluoroaluminocalciumsilicate-based, Nanoseal (NS) desensitizers on dentin tubule occlusion, inhibition of Streptococcus mutans (S. mutans) biofilm growth, and resistance to bacterial demineralization. Desensitizers were applied to simulated hypersensitive bovine dentin, with distilled water used as a control. S. mutans biofilms were grown on the surface of each specimen in an oral biofilm simulator. CS showed the least bacterial count and water insoluble glucan amount followed by NS. Transverse micro radiography revealed that both CS and NS showed significant reduction in mineral loss and lesion depth of the associated lesion. Scanning electron micrographs showed that the two desensitizers formed obvious depositions on the dentin surfaces, occlusion of tubules and mineral tag formation.

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© 2019 The Japanese Society for Dental Materials and Devices
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