2006 Volume 15 Issue 3 Pages 91-94
This is a rare case report of a dog with acquired myasthenia gravis which developed after hypothyroidism. A three-year-old golden retriever showed an abnormal manner of walking after physical exercise such as climbing up the stairs, and diagonal walking had started about 20 days before. Clinical signs and measurement of the concentration of thyroid hormone led to a diagnosis of myopathy caused by hypothyroidism. The dog was treated with thyroxine, and the clinical signs improved. But seven days later the dog had a relapse. Therefore, the dog was tested with neostigmine, a colinesterase inhibitor, and antibodies to cholinergic receptors were measured; this established a diagnosis of acquired myasthenia gravis following hypothyroidism.