Correlation Between Central Venous Pressure and Hematocrit in Dogs During Hepatectomy

Abstract

The objective of this study was to assess correlation between the changes in the central venous pressure (CVP) and hematocrit (HCT) to estimate blood loss in dogs during hepatectomy. Medical records of dogs who underwent elective hepatectomy to treat hepatic mass lesion at the Veterinary Teaching Hospital, Nippon Veterinary and Life Science University from August 2017 to July 2018, were retrospectively investigated. Data of five client-owned dogs (4 females and 1 male) aged 10-13 years (average age, 12.2 years) were included in this study. The parameters recorded during hepatectomy included esophageal temperature, heart rate, respiratory rate, arterial blood pressure, hemoglobin oxygen saturation, end-tidal carbon dioxide, end-tidal isoflurane, volume of lactated Ringer's solution, and CVP. Maximum, minimum, and mean values of CVP were investigated. Preoperative and postoperative HCT levels were 34.0 ± 2.4% and 20.0 ± 3.1%, respectively, suggesting that the HCT levels significantly reduced after hepatectomy (p=0.0033). Pearson’s correlation coefficient between maximum changes in CVP and HCT levels was 0.8792 (p=0.0495). No significant correlations were identified among other variables. In this study, CVP influenced changes in HCT levels associated with bleeding in dogs undergoing hepatectomy.