2020 Volume 29 Issue 1 Pages 25-29
An 8-year-old female mongrel dog was referred to our hospital for leukocytosis and splenomegaly. A complete blood count (CBC) showed neutrophilic leukocytosis with left shift. Hyperplastic cellularity was present in the bone marrow. There was no increase in blast cells or morphological abnormalities. The possibility of other disorders such as reactive leukocytosis was excluded. X-chromosome inactivation pattern (XCIP) analysis was performed. Clonality was detected in the peripheral blood cells and bone marrow. The dog was diagnosed with chronic myelogenous leukemia (CML). The dog was in good condition without treatment.