Journal of Animal Clinical Medicine
Online ISSN : 1881-1574
Print ISSN : 1344-6991
ISSN-L : 1344-6991
Case Report
A Canine Case of Chronic Myelogenous Leukemia
Mai ASANOAkitada TOMITAYuki SHOJITakuya KANDAAi KISHIDAKohe KISHIDASatoshi MATSUURAAtsushi HASHIMOTOMako OTSUKAAkina MIYAMOTOTetsuya SHIMODAYuji FUJII
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Keywords: canine, CML, XCIP Analysis
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2020 Volume 29 Issue 1 Pages 25-29

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Abstract

An 8-year-old female mongrel dog was referred to our hospital for leukocytosis and splenomegaly. A complete blood count (CBC) showed neutrophilic leukocytosis with left shift. Hyperplastic cellularity was present in the bone marrow. There was no increase in blast cells or morphological abnormalities. The possibility of other disorders such as reactive leukocytosis was excluded. X-chromosome inactivation pattern (XCIP) analysis was performed. Clonality was detected in the peripheral blood cells and bone marrow. The dog was diagnosed with chronic myelogenous leukemia (CML). The dog was in good condition without treatment.

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© 2020 Japanese Society of Clinical Veterinary Medicin
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