アルコールのエネルギー代謝に関する研究 (第3報)
アルコールと労働代謝との関係について
1961 年 19 巻 4 号 p. 177-181
詳細
1961 年 19 巻 4 号 p. 177-181
This experiment was carried out for purpose of knowing whether alcohol calorie is utilized or not for the muscular work. Four healthy adult men were subjected to the following experimental status, i. e., working after alcohol administration, working at fasting status without alcohol intake and resting status after alcohol administration. In comparison of each result at these experimental status the relation of the muscular work to the alcohol metabolism were discussed.
The muscular work of about 2800 to 4300 kilogrammeter per minute were loaded for 40 minutes by using the bicycle-ergometer, and amounts of individual work were regulated in the same level at the both alcohol intake and fasting status. The load of work at alcohol intake status was made an hour after alcohol was administered. A dose of alcohol was 0.5gm. per kg. body weight. The expired air was collected every 30 minutes and blood and urine sampling was made every one hour up to 5 hours after alcohol administration.
The redults summarized were as follows:
1) The decrease of alcohol concentration in blood during working hour, i. e., the difference between the first and second hour values after alcohol intake, averaged 19.6mg %, which was corrected by subtracting the excess of alcohol excretion in expired air increased by working. This value was much greater than that of 5.5mg% in resting status.
2) “β” factor calculated in lapse of 5 hours after alcohol intake averaged 11.8mg% per hour at working Status, this value was about 36% higher compared with 8.7mg% per hour at resing status. “γ” factor showed no significant difference between both status. “ED” mean value of 4.96gm. per hour at working status was about 40% higher than 3.56gm. per hour at resting status. The increasing rate of “ED” values due to working correlated with intensity or calorie consumption of work (table 1 & 2).
From the above results, it is considered that alcohol metabolism rises with working and alcohol calorie is utilized for the muscular work.
