放射性Srの排泄とCa摂取量との関係について (第2報)

抄録

In continuance to the previous report, the relation between Ca intake and ⁹⁰Sr excretion was investigated with young albino rats.
Experimental: 16 immature albino rats weighing about 70g were subjected to this experiment, and they were divided into two groups.
The 1st group was fed with a high Ca diet (506mg%) and the 2nd group on a low Ca diet (86mg%). Radioisotope was administered by the single shot method i. e., only ⁹⁰Sr was injected into the abdominal cavity of the rats, 1μc per capita.
After the injection, urine and feces of the rats were collected every two days during the first 10days, thereafter both were collected occasionally. Ten days after the injection, a tip part of the tail of each rat was cut off for the estimation of retained amount of RI in bones, 60-65days after the injection the rats were killed and the one side hind leg, incisor were taken off for determination of deposit activity in hard tissue.
Results: The amount of ⁹⁰Sr excreted by the rats fed on the high Ca diet were higher than that of the low Ca fed group.
The retained amount of ⁹⁰Sr in hard tissue, especially, in the teeth was larger in the low Ca group than that of the high Ca group.