γ-アミノ酪酸高含有カボチャ製品の血圧上昇抑制作用について

抄録

Gamma-amino butyric acid (GABA) is known as a substance for improving the blood pressure condition. The inhibiting effect on blood pressure elevation of vegetables with a high content of GABA was verified by applying pumpkin products, which contain a high GABA content, to spontaneously hypertensive rats (SHRs) and then studying the change in blood pressure under salt stress. During the four-week experimental period, the blood pressure of SHRs in the untreated control group initially increased from 142mm of Hg to 185mm of Hg and then increased further to 220mm of Hg under salt stress. In the pumpkin-administered group, the blood pressure increased from 190mm of Hg to 214mm of Hg under salt stress, indicating an inhibiting effect. A difference in the degree of inhibition was noted in different pumpkin products, even though they had the same GABA content.