Endocrinologia Japonica
Online ISSN : 2185-6370
Print ISSN : 0013-7219
ISSN-L : 0013-7219
Effect of Phospholipids on Estrogen Receptor of Rat Uterine Cytosol
NAOKI MITSUHASHIHIDEMI SIOTSUOSAMU TSUTSUMIMASAHIKO MIZUNO
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1988 年 35 巻 5 号 p. 759-762

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Phospholipids such as phosphatidyl inositol and phosphatidyl serine inhibit the binding of R5020 and progestin receptors. The effect of phospholipids on the binding of estrogen and estrogen receptors of rat uterine cytosol was studied. Phosphatidyl choline, sphingomyelin, phosphatidyl inositol, phosphatidyl ethanolamine, cardiolipin, and phosphatidic acid inhibited the binding of estradiol and estrogen receptors. This inhibitory effect of phosphatidyl inositol and cardiolipin was dose dependent.
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© The Japan Endocrine Society
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