A Case of Hypothalamic Adrenal Insufficiency Manifested Normal ACTH Response to Insulin-Induced Hypoglycemia

GOJI HASEGAWA; EISHI ASHIHARA

doi:10.1507/endocrj.47.51

Endocrine Journal

Online ISSN : 1348-4540
Print ISSN : 0918-8959
ISSN-L : 0918-8959

A Case of Hypothalamic Adrenal Insufficiency Manifested Normal ACTH Response to Insulin-Induced Hypoglycemia

GOJI HASEGAWA, EISHI ASHIHARA

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Keywords: ACTH, Hypothalamic adrenal insufficiency

JOURNAL FREE ACCESS

2000 Volume 47 Issue 1 Pages 51-55

DOI https://doi.org/10.1507/endocrj.47.51

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Abstract

A low plasma ACTH response to insulin-induced hypoglycemia and an exaggerated and delayed plasma ACTH response to CRH stimulation have been considered as an indicator of hypothalamic hypopituitarism. We report a case of hypothalamic adrenal insufficiency which manifested normal ACTH response to insulin-induced hypoglycemia. This case provides important information to categorize hypothalamic adrenal insufficiency caused by abnormal regulation of CRH release.

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