Experimental Animals
Online ISSN : 1881-7122
Print ISSN : 1341-1357
ISSN-L : 0007-5124
Original
Microbiological survey of Korean mouse facilities from 2014 to 2019
Sang Woon KimHi Jo ShinSe Hee ParkTeak Chang LeeHae Jin LeeOk Sung MoonKi Hoan NamWon Kee YoonHyoung Chin KimHyo Jung KwonYoung Suk Won
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JOURNAL OPEN ACCESS

2022 Volume 71 Issue 1 Pages 109-115

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Abstract

We surveyed mouse microbiological contamination rates by testing rates for common contaminants using serological, culture, and parasitological methods. A total of 21,292 experimentally housed mice from 206 animal facilities, including hospitals, universities, companies, and research institutes, were tested over a 6-year period from 2014 to 2019. The most commonly found contaminants were various species of nonpathogenic protozoa (47.2%). The most common pathogenic bacteria were Staphylococcus aureus (21.2%), Pasteurella pneumotropica (12.5%), and Pseudomonas aeruginosa (5.8%). Mouse hepatitis virus (6.1%) was detected, but no other viral or bacterial pathogens were found. These results establish that the main pathogens that currently contaminate mouse facilities in Korea are opportunistic pathogens and that contamination with important pathogens, such as those in Categories B or C, has decreased.

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© 2022 Japanese Association for Laboratory Animal Science
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