Experimental Animals
Online ISSN : 1881-7122
Print ISSN : 0007-5124
Brain Deformation Caused by Hyperplasia Molar Teeth (Macrodonts) in the Japanese Field Vole (Microtus montebelli)
Shoei SUGITAOsamu UCHIUMIKatsuhiko FUJIWARAShumpei NIIDAKatsuhiro FUKUTA
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JOURNAL FREE ACCESS

1994 Volume 43 Issue 5 Pages 769-772

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Abstract

Protrusion of hyperplastic upper molar teeth (macrodonts) into the cranial cavity was observed in the Japanese field vole. Protrusions of the upper molars occurred on both sides, but were large on the left than on the right. The teeth invaded the cranial cavity and brain parenchyma. Large concavities on the ventral side of the brain were interposed between the lateral olfactory tract and the optic tract. Invation by one macrodont reached the basal nuclei, hypothalamic and thalamic nuclei. The brain was deformed bilaterally, and nearly the entire olfactory bulb, globus pallidus, internal capusule, and lateral preoptic nucleus, and a portion of the hypothalamus, thalamus and anterior commissure were absent on the left side.

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© Japanese Association for Laboratory Animal Science
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