日本薬理学雑誌
Online ISSN : 1347-8397
Print ISSN : 0015-5691
ISSN-L : 0015-5691
医薬品の薬効評価とその作用メカニズムの解明
医薬品開発の国際化における薬理学の役割
長尾 拓
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ジャーナル フリー

1999 年 113 巻 1 号 p. 15-18

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In recent years, drugs developed in Japan are used internationally in other countries. The pharmaceutical pre-clinical phase is critical in the drug developing cycle. Pharmacologists contribute to finding the leading compounds and evaluate the right compound for clinical trial. The selection of the right compound for development will save both time and money. In the pharmacological evaluation of a development candidate, in vivo animal studies that can assure the clinician that the drug is both effective and safe are usually required. Studies on the mechanism of action of the drug and how the drug works in the diseased state becomes important since a known target molecule usually serves as the basis for the development of a new drug.

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© 社団法人 日本薬理学会
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