日本薬理学雑誌
Online ISSN : 1347-8397
Print ISSN : 0015-5691
ISSN-L : 0015-5691
芳香族アミノ並にニトロ化合物類の中毒に關する實驗的研究
第7報 メトヘモグロビン形成理論に關する一考察
赤堀 和一郎
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1954 年 50 巻 4 号 p. 422-432,en29

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Methemoglobin formation after the aromatic amino- or nitro-compounds was proved by the spectroscopic investigations following with the lapse of time of observations and its mechanism was explained on the basis of electrotonic theory with reference to the literatures of other authors ever published. On his opinion Fe··in hemoglobin will be oxidized to Fe··· directly or indirectly due to the electrotonic potency of available drugs tested and thus methemoglobin will be formed by neutralization of the increased charges of Fe ion with OH- in the solution.

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