日本薬理学雑誌
Online ISSN : 1347-8397
Print ISSN : 0015-5691
ISSN-L : 0015-5691
t-π-Oxocamphorの作用機序に關する實験的研究
第1報 t-π-Oxocamphor及び諸種アルデヒド類の脱水素酵素作用に及ぼす影響に就て
森田 淑子
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ジャーナル フリー

1955 年 51 巻 2 号 p. 91-93,en11

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抄録
The effect of aldehydes, including d-trans-7-aldehyde-π-apocamphor (vitacamphor), on the activity of dehydrogenase of rat tissue homogenates and of bovine heart muscle pulp was observed. The aldehydes such as vitacamphor, 10-oxocamphor, benzaldehyde, anisaldehyde and furfural, considerably decreased the activities of dehydrogenases of the brain and heart homogenates, and of lactic and citric dehydrogenase of the heart. Vitacamphor showed less inhibitory effect on these enzymes of the kidney and liver than other aldehydes. Two aldehydes, cinnamic aldehyde and citral, caused a strong inhibition on the dehydrogenase of tissue homogenates and lactic, citric and some other dehydrogenases, while citronellal, heptaldehyde and acetaldehyde showed only slight effects on dehydrogenase activities.
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