N-Acetyl-L-glutamine aluminum complex (KW-110) was studied with regard to the effects on various experimental ulcers. As a result, KW-110 showed antiulcerogenic action against all of the ulcers studied. Preventive effects against stress ulcer and Shay rat ulcer were especially remarkable. Moreover curative effect was also confirmed in acetic acid ulcer. From the studies of the other pharmacological properties, KW-110 showed inhibition of gastrointestinal motility, rise of gastric juice pH, and decrease of spontaneous movement. No other pharmacological action was observed.
