Abstract
Transcatheter Arterial Embolization (TAE) and Intra-Arterial one shot Injection Therapy (TAT) were performed to treat patients with primary hepatoma. TAE was performed in 15 patients, TAT in 11. Gastroduodenal endoscopic examination was carried out in every case before and after TAE or TAT. Preexisting gastroduodenal ulcers did not worsen after therapy. The incidence of gastroduodenal lesions and symptoms was signifi-cantly higher after TAE than after TAT (P<0.05 ; P <0.01) (Figures 1, 4). Chemoembolization caused much more gastroduodenal lesions than simple TAE without anti-cancer agents (P<0.05) (Figure 3). When more than 15 days passed after TAE, the incidence of gastroduodenal ulcers significantly increased (P<0.05). Cimetidine showed no prophylactic effect on gastroduodenal lesions. Results of serum amylase and abdominal echogram revealed that epigastralgia after TAE or TAT might not be correlated to pancreatitis or cholecystitis. These findings suggest that it is necessary to pay more attention to gastroduodenal lesions following TAE than following TAT, especially following chemoembolization.
