1996 Volume 38 Issue 4 Pages 1057-1062_1
A 68-year-old female was admitted to our hospital in March 1995 with the history of anemia and abdominal fullness. The endoscopic examination showed Barrett's esophagus (BE) with esophageal hiatal hernia. The squamo-columnar mucosal junction was clearly demonstrated determined defined in the middle esophagus. And we could observe the micro-pattern of the BE mucosa. The length of BE was 7cm. Biopsy specimens obtained from the lesion demonstrated regenerating columnar epithelium with goblet cell meta-plasia. Endoscopy was initially first performed in Novembeer, 1990 at another hospital. It revealed esophageal ulcer above the lower esophageal sphincter (LES), and the creeping type of columnar epithelium was observed (2 cm from LES). Then, she had been medicated with ranitidine 300mg/day and sucralfate 4g/day. Two endoscopic examination were performed after the first endoscopy, the diagnoses were also ref lux esophagitis. Retrospec-tively, in this case, we presumed suspect that BE developed 5cm for 4.4 years. And this case was considerd an aquired disorder associated with gastro-esophageal reflux.
