Abstract
Methods : From January 2005 to December 2005, enrolled 600 patients taking low dose aspirin, in those endoscopies were performed. Results : The rate of upper gastrointestinal ulcers or hemorrhagic lesions was 7.7% in the total subjects ; 9.5% in the patients taking no anti-acid medicine, 8.7% in the H 2 receptor agonist (H2 RA) group, and 1.0% in the proton pump inhibiter (PPI) group. There was no significant correlation between finding ulcer lesions and aging over 70 years-old, or taking other anti-coagulant therapies. Conclusion : Treatment with PPI significantly reduced the rate of upper gastrointestinal ulcer and bleeding in the patients taking low dose aspirin.
