1985 Volume 22 Issue 1 Pages 47-52
We had reported that the brain atrophy progressed significantly with advancing age using the two dimensional CT measurement by digitizer which was connected with personal computer (Fig. 1). Using this method, we studied the age-related infra-tentrial brain atrophy in 67 normal subjects (14-90 years), and compared that with agerelated supra-tentrial brain atrophy.
There was a significant correlation between age and all indices [cranio-ventricular index (CVI), ventricular area index (VAT) and brain atrophy index (BAI)] in supratentrial brain. These indices did not correlated to the age in infra-tentrial brain (brainstem and cerebellum). Significant change of the brain atrophy occured above 60 years old was observed by BAI and VAI in supra-tentrial brain (Fig. 2). There was a significant correlation between supra-tentrial brain atrophy index (BAI) and that of infratentrial brain (Table 1).
These results indicate that age-related brain atrophy might progress more slowly in brainstem and cerebellum than in cerebrum.
