Effusion Cytology in Aged Patients with Malignancy

Abstract

During the last 10 years, 162 aged cases (60yrs. to 96yrs., average 75.7yrs.) that had positive effusion cytology were confirmed to have malignancy on autopsy. The effusion cytology of samples from aged patients made the first clinical diagnosis of malignancy in 46% of the cases studied, and this frequency increased with increasing age. The effusion cytology results from aged patients with malignancy were observed to have the following characteristic pathology profiles; (a). In pleural effusion: The primary organ of cancer was mostly the lung. However the histological cell types varied from predominantly adenocarcinoma to small cell carcinomas, squamous cell carcinomas etc. (b). In ascitic effusion: The primary organ of cancer varied and included the stomach, gallbladder, pancreas and ovaries. In these cases, however, the histological cell type was predominantly adenocarcinoma.