1970 Volume 7 Issue 3 Pages 168-173
Lymphosarcoma cell leukemia is an establiched clinical entity which is characterized by the presence of numerous abnormal lymphoid cells in the peripheral blood, together with the clinical signs simular to that of lymphosarcoma.
We report here an autopsied case of lymphosarcoma cell leukemia in the elderly characterized by an extensive infiltration of the tumor in the skelton.
A 68 years old man was admitted to the Department of Geriatrics, Faculty of Medicine, University of Tokyo, with the chief complaints of generalized lymphadenopathy and general malaise. Examination revealed a leukocytosis with 34.5% of abnormal lymphoid cells in the peripheral blood, completely destroyed lymph-node structure with the proliferation of abnormal reticulum-like cells and proliferation of lymphoid cells in the bone marrow. It appeared that the lymph-node was the primary site of affection and was the origin of abnormal lymphoid cells in the peripheral blood. Particularly interesting in this case was the finding of an extensive infiltration of the tumor in the entire skelton, demonstrating numerous punched out lesions of the long bones, flat bones and the skull.
