Nippon Ronen Igakkai Zasshi. Japanese Journal of Geriatrics
Print ISSN : 0300-9173
Correlation of Blood Pressure and Total Serum Cholesterol to Severity of Atherosclerosis in the Aorta, the Coronary and the Cerebral Arteries
Kazuhiko MurataFujio TerasawaJun FujiiKizuku KuramotoSaichi HosodaHiroshi KuriharaLie Hon YingSatoru MatsushitaMorio KuramochiMasao IkedaMasuji Seki
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1971 Volume 8 Issue 6 Pages 323-328

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Abstract

Macroscopic examinations were made on the aorta, the coronary and the cerebral arteries in 132 autopsy cases with long follow-up of the blood pressure and the total serum cholesterol.
A significant positive correlation was demonstrated between the average of the annual systolic pressure and the severity of atherosclerosis in the aorta (r=+0.282, p<0.05), the coronary (r=+0.319, p<0.01), and the cerebral arteries (r=+0.434, p<0.01). On the other hand, the average of the annual diastolic pressure was related only to the severity of the cerebral atherosclerosis (r=+0.284, p<0.01).
There was a significant positive correlation between the average of the total serum cholesterol and the severity of the stenosing atherosclerotic lesions of the coronary arteries (r=+0.284, p<0.01). However, the total serum cholesterol was unrelated to the severity of the atherosclerosis of the aorta and the cerebral arteries. It was also apparent that the atherosclerotic lesions in the three arteries do not progress parallel.
Basing on the above results, the necessity for detailed study on the local factors for atherogenesis was finally pointed out.

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