1971 Volume 8 Issue 6 Pages 323-328
Macroscopic examinations were made on the aorta, the coronary and the cerebral arteries in 132 autopsy cases with long follow-up of the blood pressure and the total serum cholesterol.
A significant positive correlation was demonstrated between the average of the annual systolic pressure and the severity of atherosclerosis in the aorta (r=+0.282, p<0.05), the coronary (r=+0.319, p<0.01), and the cerebral arteries (r=+0.434, p<0.01). On the other hand, the average of the annual diastolic pressure was related only to the severity of the cerebral atherosclerosis (r=+0.284, p<0.01).
There was a significant positive correlation between the average of the total serum cholesterol and the severity of the stenosing atherosclerotic lesions of the coronary arteries (r=+0.284, p<0.01). However, the total serum cholesterol was unrelated to the severity of the atherosclerosis of the aorta and the cerebral arteries. It was also apparent that the atherosclerotic lesions in the three arteries do not progress parallel.
Basing on the above results, the necessity for detailed study on the local factors for atherogenesis was finally pointed out.