Abstract
Mice of a pure strain were inoculated with the murine leprosy bacilli and treated with a light sensitive dye, Neo-cyancor 12. The following results were obtained:
1) Short term treatment with this agent shows a suppressive effect on leproma develop-ment but long-term treatment has an enhancing effect.
2) Excision and accurate measurement of the leproma verifies the above; the leproma being significantly smaller than the control in the short term treatment group and larger in the long-term treatment group.
3) Histological examination of the leproma with the fluorescent microscope shows that the form of many of the murine leprosy bacilli is altered in the treated group and disrupted forms incaease parallel with treatment. This shows that there is no relationship between the therapeutic progress and appearance of abnormal forms.
4) There was no significant difference in the number of bacilli present in the leproma between the treated and control groups.
