抄録
Cycloserine was administered in a dose of 1.0 mg daily, 6 days a week for 120 days in mice inoculated with a small quantity or large quantity of murine leprosy bacilli and the effect compared to that in the untreated control.
No effect was noted in the groups inoculated with either the small or large quantity of bacteria and no difference due to the dose of cycloserine was found. In other words, there was no difference between the treated group and the untreated control. From the results, it is believed that this agent has no effect in murine leprosy.
The results differ from those of Chang, but this may be attributed to the difference in experimental methods. A universal standard screening method should be set up as soon as possible.
