Measurement of estimated glomerular filtration rate is useful in stroke patients

Abstract

Background: Chronic kidney disease (CKD) is a major worldwide public health problem. Although CKD is widely known to cause stroke, evaluation of renal function in stroke patients is difficult.
Purpose: We aimed to determine the prevalence of CKD in stroke patients and demonstrate the validity of estimated glomerular filtration rate (eGFR) measurement to assess renal function in patients after stroke.
Subjects and Methods: We examined the prevalence of CKD in 545 stroke patients and assessed correlations between eGFR and biochemical data, prevalence of hypertension, diabetes mellitus, hypercholesterolemia, and atrial fibrillation (AF).
Results: Of the 545 patients, 178 (32.8%) had CKD with a low eGFR ( <60 mL/min/1.73 m²). eGFR was negatively correlated with age, serum uric acid and creatinine concentrations, and positively correlated with hemoglobin levels. Moreover, eGFR was correlated with the prevalence of hypertension and AF, but not diabetes mellitus or hypercholesterolemia.
Conclusions: High prevalence of CKD was observed in stroke patients. Measurement of eGFR can be useful in evaluating renal function in stroke patients.