広島商船高等専門学校研究報告書:Annual report
Online ISSN : 2760-0416
アミノ酸の出現パターンにもとづくタンパク質の配列特徴解析
加藤 博明
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研究報告書・技術報告書 フリー

2025 年 1 巻 p. 23-29

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It is well known that the amino acid sequence of a protein is closely related to its structure and function. In the present work, we focused on the appearance patterns of amino acids and developed the program to quantitatively evaluate the similarity between protein sequences. The processing steps are the following: (1) Characteristic patterning of sequence data, (2) Quantitative comparison using Euclidean distance, and (3) Clustering and phylogenetic tree generation. Sequence data for each hemoglobin α and β from 10 species including humans was used. As a result of creating a phylogenetic tree, we were able to successfully classify them into four groups: α birds, α mammals, β birds, and β mammals.
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