電気油圧駆動式全人工心臓の開発 —血液ポンプ駆動ユニットの改良—

本間 章彦; 妙中 義之; 巽 英介; 武輪 能明; 水野 敏秀; 塩谷 恭子; 李 桓成; 築谷 朋典; 角田 幸秀; 片桐 伸将; 西中 知博; 越地 耕二

doi:10.1541/ieejeiss.128.943

Development of an Electrohydraulic Total Artificial Heart System

—Improvement of the Pump Unit—

Akihiko Homma, Yoshiyuki Taenaka, Eisuke Tatsumi, Yoshiaki Takewa, Toshihide Mizuno, Kyoko Shioya, Hwan Sung Lee, Tomonori Tsukiya, Yukihide Kakuta, Nobumasa Katagiri, Tomohiro Nishinaka, Kohji Koshiji

Author information

Akihiko Homma
The Advanced Medical Engineering Center, Research Institute, National Cardio Vascular Center
Yoshiyuki Taenaka
The Advanced Medical Engineering Center, Research Institute, National Cardio Vascular Center
Eisuke Tatsumi
The Advanced Medical Engineering Center, Research Institute, National Cardio Vascular Center
Yoshiaki Takewa
The Advanced Medical Engineering Center, Research Institute, National Cardio Vascular Center
Toshihide Mizuno
The Advanced Medical Engineering Center, Research Institute, National Cardio Vascular Center
Kyoko Shioya
The Advanced Medical Engineering Center, Research Institute, National Cardio Vascular Center
Hwan Sung Lee
The Advanced Medical Engineering Center, Research Institute, National Cardio Vascular Center
Tomonori Tsukiya
The Advanced Medical Engineering Center, Research Institute, National Cardio Vascular Center
Yukihide Kakuta
The Advanced Medical Engineering Center, Research Institute, National Cardio Vascular Center
Nobumasa Katagiri
The Advanced Medical Engineering Center, Research Institute, National Cardio Vascular Center
Tomohiro Nishinaka
Department of Cardiovascular Surgery, Tokyo Women's Medical University
Kohji Koshiji
Tokyo University of Science, Faculty of Science and Technology

Keywords: electrohydrauric total artificial heart, blood pump, brushless DC motor, transcutaneous energy transfer system (TETS), transcutaneous optical information transfer system (TOTS)

JOURNAL FREE ACCESS

2008 Volume 128 Issue 6 Pages 943-952

DOI https://doi.org/10.1541/ieejeiss.128.943

Details

Abstract

An electrohydraulic total artificial heart (EHTAH) system has been developed. The EHTAH system consists of diaphragm-type blood pumps, an electrohydraulic actuator, an internal control unit, a transcutaneous energy transfer system (TETS), a transcutaneous optical telemetry system (TOTS), and an internal battery. The reciprocating rotation of the impeller generates oil pressure which drives the blood pumps at alternating intervals. The blood pumps and the actuator were successfully integrated into the pump unit without oil conduits. As a result of miniaturizing the blood pumps and the actuator, the displacement volume and weight of the EHTAH system decreased to 872 ml and 2492g, respectively. Furthermore, the maximum flow rate and efficiency increased up to 12 L/min and 15.4%. The pump units and the EHTAH systems were successfully implanted in 36 calves weighing from 55 to 87kg. In the longest case, the ca1f with the pump unit survived for 87 days and the calf with the EHTAH system survived for 70 days. The EHTAH system was powered by the TETS, and was powered everyday by the internal battery for 40 minutes. These results indicate that the EHTAH system has the potential to become a fully implantable cardiac replacement system.

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