電気学会論文誌C(電子・情報・システム部門誌)
Online ISSN : 1348-8155
Print ISSN : 0385-4221
ISSN-L : 0385-4221
<生体医工学・福祉工学>
ウェアラブル式空気圧駆動装置の全置換型人工心臓システムへの応用の基礎的検討
住倉 博仁本間 章彦大沼 健太郎妙中 義之武輪 能明梅木 昭秀水野 敏秀築谷 朋典片桐 伸将藤井 豊角田 幸秀向林 宏片野 一夫福井 康裕巽 英介
著者情報
ジャーナル 認証あり

2014 年 134 巻 6 号 p. 839-847

詳細
抄録

We have been developing a wearable pneumatic total artificial heart (PTAH) system for bridge to transplant, and we evaluated its fundamental performance in in vitro and in vivo experiments. The PTAH system consists of left and right diaphragm-type blood pumps and a compact wearable pneumatic drive (WPD-100) unit. The WPD-100 unit can generate a fixed systole ratio by the non-circular gears. The prototype WPD-100 units with fixed systolic ratio of 35, 40 and 44% were developed. 25 mm and 23 mm Bicarbon valves were mounted in the inlet and outlet ports of the left and right blood pumps. As a result of an overflow-type mock circulation test, more than 8.0 l/min of pump output was obtained at 100 bpm for after load of 80, 100 and 120 mm Hg in all WPD-100 units. An acute animal experiment was also performed using WPD-100 units with fixed systolic ratio of 35 and 44% in a calf weighing 98 kg. The cardiac output ranged between 4.3 and 5.2 l/min at the mean aortic pressures of 108-115 mm Hg at beating rates of 60 to 100 bpm. These results indicated that our PTAH system consisting of two blood pumps and WPD-100 units have sufficient performance for total cardiac replacement.

著者関連情報
© 2014 電気学会
前の記事 次の記事
feedback
Top