歯科材料中の新規毒性化合物に関する研究

抄録

Methyl methacrylate polymer (PMMA) is widely used as the dental plate. After fabrication of PMMA, methacrylate monomer, benzoylperoxide, N, N'-dimethyl ρ-toluidine used for starting reagents were remained. These were toxic and the residue of these compounds as well as time course of elution were already reported. In addition to these compounds, newly found toxic compounds with hydrophilic characteristics were identified and determined the amount eluted in human saliva, so analytical procedure of these compounds using high performance liquid chromatography-mass spectrometry combined with ultrafiltration is presented.