Industrial Health
Online ISSN : 1880-8026
Print ISSN : 0019-8366
ISSN-L : 0019-8366
Case Report
Myoclonic Encephalopathy after Exposure to Trichloroethylene
Pere SANZSantiago NOGUÉDaniel VILCHEZElisa SALVADÓAmparo CASALGiancarlo LOGROSCINO
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2008 Volume 46 Issue 6 Pages 635-637

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Abstract

Trichloroethylene is a widely-used industrial solvent that is absorbed through the digestive or respiratory tracts or cutaneously. It has a selective tropism for the cardiovascular and central nervous systems and may cause death due to cardiac arrest or neurological sequelae.
We present the case of a 25-yr-old women who was exposed to trichloroethylene in the workplace for 18 months and who developed a disabling myoclonic encephalopathy. Non-toxicological causes were excluded. Although the exposure ceased, the disease progressed with thalamic and cerebellar involvement. The patient, who had only a partial response to symptomatic treatment, suffered severe limitations in the activities of daily living and was registered as permanently disabled due to a work-related disability.

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© 2008 by National Institute of Occupational Safety and Health
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