The role of infection (Candida albicans) in modifying the fibro-genesis caused by a fibrous platy silicate (talc) and a particulate silicate (kaolin) was studied in the lungs of guinea pigs over a period of 180 days. Kaolin was found to be more fibrogenic in the presence of Candida albicans than the talc. The enhanced fibrogenicity has been attributed to the adjuvant activity of kaolin with polysaccharide glucan component of candida.
