Industrial Health
Online ISSN : 1880-8026
Print ISSN : 0019-8366
ISSN-L : 0019-8366
Five-tesla Static Magnetic Fields Suppress Food and Water Consumption and Weight Gain in Mice
Yoko TSUJIMasayoshi NAKAGAWAYuji SUZUKI
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1996 Volume 34 Issue 4 Pages 347-357

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Abstract

In this study, the effects of 5-tesla (T) static magnetic fields (SMFs) on food and water intake in BALB/c mice were examined. We also examined body weight changes, organ weights and some serum biochemical parameters to evaluate the physiological changes resulting from changes in food and water intake.
Mice were exposed to 5-T SMFs for 24h and 48h. Food intake, water intake and the mean body weight of mice tended to decrease after 24h of exposure to SMFs (p=0.054, p=0.119, p=0.107, respectively). Those parameters decreased significantly after 48h of exposure (p=0.039, p=0.0003, p=0.009, respectively). These results suggested a positive relationship between the duration of exposure, and the responses, represented by food intake, water intake, and body weight of the mice. However, the weights of brain, lungs, heart, liver, spleen, and kidneys did not change after 48h of exposure. The blood urea nitrogen (BUN) levels and blood glucose levels increased significantly after 48h of exposure (p=0.03, p=0.005, respectively). The BUN-to-creatinine (BUN/Cr) ratio tended to increase after 48h of exposure (p=0.07).
We conclude that exposure to 5-T SMFs for 48h suppresses eating and drinking behavior. We considered that the decreased body weight, increased BUN levels and slightly increased BUN/Cr ratio after 48h of exposure to 5-T SMFs were due to body fluid loss resulting from decreased food and water intake.

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