1996 Volume 34 Issue 4 Pages 403-407
LC50 of 2-bromopropane was reexamined by using the OECD guideline in ICR mouse. The mice, 3 males and 3 females, were exposed to 2-bromopropane at five different concentrations for 4h in inhalation chambers. The exposed animals were observed for 14 days. The animals which had survived and died were counted for the LC50 determination. The LC50 was calculated by using a dose-mortality curve at a 95 percent confidence level. The LC50 was 31, 171ppm, and the lowest lethal concentration (LLC) was lower than 29, 528ppm and the lethal concentration at 100% (LC100) was higher than 32, 905ppm.