STUDIES ON LYSOZYME I

EFFECT OF AZO-COUPLING ON BIOLOGICAL ACTIVITY OF LYSOZYME

Abstract

Hen egg white Iysozyme was azo-coupled with benzene sulfonic acid diazonium salt-S³⁵. The coupling reaction introduced azo groups mainly to lysyl residues and partly to tyrosyl residues. It caused the change of the biological activity of lysozyme. The lytic activity was effected with the azo-coupling, but the hydrolytic activity was not.