Internal Medicine
Online ISSN : 1349-7235
Print ISSN : 0918-2918
ISSN-L : 0918-2918
Gastrointestinal Diseases
Ulcerative Colitis Occurring in the Course of Rheumatoid Arthritis: A Case Successfully Treated with Mesalamine Enema
Kota SUGISAKIFumiko HONMAHaruyo IWADATEKiori SHIOYasuo SHIOYAEtsuko FUKAYAKaoru SATOHiroyuki SAITOHideharu SEKINEHiroko KOBAYASHIHiroshi ORIKASAHiroshi WATANABEYukio SATO
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JOURNALS OPEN ACCESS

2004 Volume 43 Issue 11 Pages 1046-1050

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Abstract

We report a case of ulcerative colitis (UC) that occurred during the course of rheumatoid arthritis (RA). A 29-year-old woman with a 25-year history of RA was hospitalized for high fever, abdominal pain and hematochezia. Colonoscopy revealed erosive and reddish mucosa from the distal transverse colon to rectum. Histology revealed cryptitis (mainly caused by neutrophils), mild crypt abscess and goblet cell depletion. She was diagnosed with left-sided UC and treated with mesalamine enema. The abdominal symptoms and colonoscopic findings were greatly ameliorated. We conclude that the mesalamine enema was effective in this case of UC occurring during the course of RA.

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© 2004 by The Japanese Society of Internal Medicine
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