Internal Medicine
Online ISSN : 1349-7235
Print ISSN : 0918-2918
ISSN-L : 0918-2918
Cardiovascular Diseases
Efficacy of Steroid Therapy for Pacing Failure in a Patient with Chronic Myocarditis
Nobuyuki MITSUYARyoji KISHINoriyuki SUZUKIMasachika TAMURAYukiko IMAIOsamu TANAKAAkihiko TAKAGIKiyoshi NAKAZAWAFumihiko MIYAKESachihiko NOBUOKAJyunki KOIKE
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JOURNAL OPEN ACCESS

2004 Volume 43 Issue 3 Pages 213-217

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Abstract

A 66-year-old man had a progressive increase in the pacing threshold over a one-year period, resulting from chronic myocarditis. Following steroid therapy, the pacing threshold decreased and became stabilized, and was accompanied by a decrease in the serum creatine kinase, cardiac myosin light chains and pro-collagen III peptide values, but cardiac function did not improve. Endocardial biopsy showed that there was no progression in the fibrosis. The pacing failure improved, but the cardiac function did not. It was believed that the steroid therapy suppressed the progression of the inflammation and fibrosis caused by the chronic myocarditis.

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© 2004 by The Japanese Society of Internal Medicine
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