Internal Medicine
Online ISSN : 1349-7235
Print ISSN : 0918-2918
Infectious Diseases
Typhoid Fever as a Rare Cause of Hepatic, Splenic, and Bone Marrow Granulomas
Ali MERTFehmi TABAKResat OZARASRecep OZTURKHilal AKIYildirim AKTUGLU
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JOURNALS OPEN ACCESS

2004 Volume 43 Issue 5 Pages 436-439

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Abstract

During the course of typhoid fever, the usual histologic finding of the liver is “nonspecific reactive hepatitis.” Hepatic granuloma (HG) is a rare complication of typhoid fever. We present two cases of typhoid fever with HG and review the relevant literature. Case 1 (a 53-year-old female) was found to have both hepatic and splenic granulomas. This is the first case of typhoid fever with splenic granulomas in the English language literature. Case 2 (a 66-year-old male) developed granulomas in the bone marrow in addition to HG. It should be considered that typhoid fever may lead to granulomas in several organs.

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© 2004 by The Japanese Society of Internal Medicine
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