Internal Medicine
Online ISSN : 1349-7235
Print ISSN : 0918-2918
ISSN-L : 0918-2918
Respiratory Diseases
Three Cases of Non-specific Interstitial Pneumonia Associated with Primary Lung Cancer
Toshio SATOIchiro YAMADORIJiro FUJITANoboru HAMADAToshiro YONEIShuji BANDOHYuji OHTSUKIToshihiko ISHIDA
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JOURNALS OPEN ACCESS

2004 Volume 43 Issue 8 Pages 721-726

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Abstract

NSIP associated with primary lung cancer has been rarely reported. In the present report, three cases of histologically proven non-specific interstitial pneumonia (NSIP) associated with primary lung cancer are described. Importantly, in our 3 cases, interstitial pneumonia which is histologically proven to be NSIP was observed diffusely in both lungs. NSIP in these 3 cases responded to steroid therapy. However, 2 patients died from primary lung cancer and 1 patient died from progression of the interstitial pneumonia. Although the association between lung cancer and NSIP has been rarely documented, this combination was considered to be one of the paraneoplastic phenomena. The possible association between primary lung cancer and NSIP is discussed.

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© 2004 by The Japanese Society of Internal Medicine
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