Internal Medicine
Online ISSN : 1349-7235
Print ISSN : 0918-2918
ISSN-L : 0918-2918
CASE REPORTS
Neutropenic Enterocolitis in Lung Cancer: A Report of Two Cases and a Review of the Literature
Makoto FURONAKAMitsuru MIYAZAKIMasamistu NAKAJIMAShintaro HIRATAKazunori FUJITAKAKeiichi KONDOAkihito YOKOYAMAHiroyuki MAEDANobuoki KOHNO
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JOURNAL OPEN ACCESS

2005 Volume 44 Issue 5 Pages 467-470

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Abstract

The first patient, a 68-year-old woman, presented neutropenic fever and hemorrhagic diarrhea on the sixth day of a combination chemotherapy of carboplatin and paclitaxel. The second patient, a 30-year-old man, presented neutropenia and diarrhea on the tenth day of the second cycle of a combination chemotherapy of cisplatin and vinorelbine. In both patients, abdominal computed tomography scan showed thickening of the colon wall and pericolic edema, and the ultrasonography revealed echogenic thickening of the colon walls. These findings confirmed the diagnosis of neutropenic enterocolitis. After the treatments, we changed the anticancer drug regimen; and successfully achieved partial responses.

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© 2005 by The Japanese Society of Internal Medicine
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