Two Cases of Primary Pulmonary Osteosarcoma

Toru KADOWAKI; Hironobu HAMADA; Akihito YOKOYAMA; Hitoshi KATAYAMA; Masahiro ABE; Kazutaka NISHIMURA; Noriyuki TOMIYAMA; Katsumi KITO; Tatsuhiko MIYAZAKI; Jitsuo HIGAKI

doi:10.2169/internalmedicine.44.632

CASE REPORTS

Two Cases of Primary Pulmonary Osteosarcoma

Toru KADOWAKI, Hironobu HAMADA, Akihito YOKOYAMA, Hitoshi KATAYAMA, Masahiro ABE, Kazutaka NISHIMURA, Noriyuki TOMIYAMA, Katsumi KITO, Tatsuhiko MIYAZAKI, Jitsuo HIGAKI

Author information

Toru KADOWAKI
Second Department of Internal Medicine, Ehime University School of Medicine
Hironobu HAMADA
Second Department of Internal Medicine, Ehime University School of Medicine
Akihito YOKOYAMA
Department of Molecular and Internal Medicine, Graduate School of Biomedical Sciences, Hiroshima University
Hitoshi KATAYAMA
Second Department of Internal Medicine, Ehime University School of Medicine
Masahiro ABE
Department of Respiratory Medicine, Ehime National Hospital
Kazutaka NISHIMURA
Department of Respiratory Medicine, Ehime National Hospital
Noriyuki TOMIYAMA
Department of Radiology, Ehime National Hospital
Katsumi KITO
First Department of Pathology, Ehime University School of Medicine
Tatsuhiko MIYAZAKI
Second Department of Pathology, Ehime University School of Medicine
Jitsuo HIGAKI
Second Department of Internal Medicine, Ehime University School of Medicine

Keywords: primary pulmonary osteosarcoma, calcified pulmonary mass, technetium-99m methylene diphosphonate bone scintigraphy, needle biopsy

JOURNAL OPEN ACCESS

2005 Volume 44 Issue 6 Pages 632-637

DOI https://doi.org/10.2169/internalmedicine.44.632

Details

Abstract

Two cases of primary pulmonary osteosarcoma are presented. In both cases, chest computed tomography revealed a calcified pulmonary mass and technetium-99m methylene diphosphonate bone scintigraphy showed intense uptake in the pulmonary mass. Primary pulmonary osteosarcoma was suspected on the basis of these radiographic findings. Microscopic examination of tumor specimens obtained by needle biopsy revealed histologic features of osteosarcoma, and this diagnosis was confirmed by postmortem examination of a second specimen in each case. Radiographic and histopathological findings enabled us to diagnose primary pulmonary osteosarcoma, which is one of the rarest types of cancer.

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