Internal Medicine
Online ISSN : 1349-7235
Print ISSN : 0918-2918
ISSN-L : 0918-2918
CASE REPORTS
Sjögren’s Syndrome Associated with Chronic Hepatitis C, Severe Thrombocytopenia, Hypertrophic Cardiomyopathy, and Diabetes Mellitus
Takeshi KAMIMURAHidetomo SATOMasahiro IWAMOTOHiroyuki NARAKimiaki TORIKOEJun-Ichi MASUYAMAHitoaki OKAZAKISeiji MINOTA
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JOURNALS OPEN ACCESS

2005 Volume 44 Issue 6 Pages 657-661

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Abstract

A 74-year-old woman with Sjögren’s syndrome and chronic hepatitis C (CHC) was admitted to our hospital in October 2003 for treatment of diabetes mellitus. She had the past history of recurrent thrombocytopenia, which was proven to be due to peripheral destruction. Although she had been diagnosed with hypertrophic cardiomyopathy (HCM) for 2 years, she had never felt palpitation. She suddenly died probably of fatal arrhythmia related to HCM during the last hospitalization. Although hepatitis C virus (HCV) infection has been associated with Sjögren’s syndrome, thrombocytopenia, HCM, and diabetes mellitus, all these diseases rarely occur in a single patient. It will be necessary to identify similar cases to elucidate the etiopathogenesis of extra-hepatic manifestations of HCV infection.

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© 2005 by The Japanese Society of Internal Medicine
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